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In 'The Hangover,' Ed Helms plays Stu Price, a mild-mannered dentist who unexpectedly becomes embroiled in the wild and chaotic aftermath of a bachelor party in Las Vegas. This role marked a significant shift in Helms's career, showcasing his ability to blend physical comedy with a neurotic charm, contrasting with his earlier more subdued or supporting roles, such as his work on 'The Office.' Helms's performance stood out for its balance of humor and vulnerability, contributing to the film's dynamic ensemble and propelling him into the spotlight as a leading comedic actor. Compared to his previous work, Stu Price allowed Helms to explore a broader comedic range and solidify his place in mainstream comedy cinema.

Zach Galifianakis played the character Alan Garner in the 2009 comedy film 'The Hangover.' His performance was widely praised for its quirky and deadpan humor, which brought a unique charm to the film. Galifianakis's portrayal of Alan, a socially awkward and unpredictable character, stood out as one of the most memorable aspects of the movie, contributing significantly to its success. One lesser-known fact about his involvement is that much of his dialogue was improvised; Galifianakis enjoyed adding spontaneous, offbeat lines that enhanced the authenticity and unpredictability of his character, which delighted both the cast and crew on set.

In the movie 'The Hangover,' Sasha Barrese played the role of Tracy Billings, who is the fiancée of Ed Helms' character, Stu Price. Her character serves as a grounding force and a source of emotional stability amidst the chaos of the film's wild bachelor party storyline. This role stands out in Barrese's career as it placed her in a major, widely successful comedy that gained significant cultural popularity. Compared to her earlier work, which often included smaller parts or roles in less mainstream projects, her performance in 'The Hangover' brought her greater visibility and showcased her comedic timing in a high-profile ensemble cast.