Splice

"Splice" is a thrilling sci-fi horror film that follows Elsa and Clive, two young rebellious scientists who push the limits of legal and ethical science by splicing human and animal DNA together. They create a new organism named "Dren," who quickly evolves from a deformed infant into a beautiful yet dangerous winged human-chimera. Dren forms complex bonds with her creators, which eventually take a deadly turn.

Trivia:
1. The creature Dren was portrayed by multiple performers, including actress Delphine Chaneac, who wore extensive prosthetics and a prosthetic tail to bring the hybrid character to life.
2. The film's director, Vincenzo Natali, wanted to explore the moral ambiguities of genetic engineering, and the script was designed to provoke thought about the consequences of playing God.
3. "Splice" features practical effects combined with CGI to create realistic and unsettling creature designs, earning praise for its innovative blend of techniques in creature creation.

Full Cast of Splice

Crew of Splice