In a San Francisco basement, physics post-graduate student Quinn Mallory has found a way to create portals to parallel universes. Inviting his physics professor Maximillian Arturo and his computer store colleague Wade Wells for a trip, a series of mishaps ropes in passing singer Rembrandt Brown and takes the Sliders off their planned route. Upon discovering a frozen world and one where Russia rules America, the quartet begins to doubt that they will be able to return to their own world anytime soon...