Meet the Cast of I Know This Much Is True

The parallel lives of identical twin brothers Dominick and Thomas Birdsey in an epic story of betrayal, sacrifice and forgiveness set against the backdrop of 20th century America.

Main Cast of I Know This Much Is True

Mark Ruffalo

as Dominick Birdsey / Thomas Birdsey (6 episodes)

Mark Alan Ruffalo (born November 22, 1967) is an American actor and producer. He began acting in the early 1990s and ...

Melissa Leo

as Concettina Ipolita Tempesta 'Ma' Birdsey (6 episodes)

Rosie O'Donnell

as Lisa Sheffer (6 episodes)

Roseann "Rosie" O'Donnell (born March 21, 1962) is an American stand-up comedienne, actress, singer, author and media...

Archie Panjabi

as Dr. Patel (6 episodes)

Kathryn Hahn

as Dessa Constantine (6 episodes)

Kathryn Marie Hahn (born July 23, 1973) is an American actress and comedian. She began her career on television, star...

John Procaccino

as Ray Birdsey (6 episodes)

Rob Huebel

as Leo (6 episodes)

Rob Huebel (born June 4, 1969) is an American actor, comedian and writer best known for his sketch comedy work on the...

Michael Greyeyes

as Ralph Drinkwater (6 episodes)

Michael Greyeyes is an actor, dance artist, choreographer and writer.

Secondary Cast of I Know This Much Is True

Harris Yulin

as Father Lavie (1 episode)

Harris Yulin (born November 5, 1937) is an American actor.

Bruce Greenwood

as Dr. Hume (2 episodes)

Stuart Bruce Greenwood (born August 12, 1956) is a Canadian actor and producer. He is known for his role as the Ameri...

Marcello Fonte

as Domenico Onofrio Tempesta (2 episodes)

Sue Jean Kim

as Dr. Yup (1 episode)

Gina Costigan

as Mrs. O'Meara (1 episode)

Steven Cox

as Boyfriend of Dr. Hume's Daughter (1 episode)

MorningStar Angeline

as Nabby Drinkwater's Wife (1 episode)

MorningStar Angeline, born as MorningStar Angeline Wilson-Chippewa Freeland, is a Navajo, Blackfoot and Mexican Ameri...

Amy Lynn Stewart

as Merciful Mother (1 episode)

Guillermo Díaz

as Sergeant Mercado (1 episode)

Marylouise Burke

as Librarian (1 episode)

Marylouise Burke was born on January 20, 1941 and is currently 84 years old.

Brian Goodman

as Al (1 episode)

From Wikipedia, the free encyclopedia. Brian Goodman is an American film and television director, writer, and actor.

Sandra Berrios

as Social Worker at Hatch (1 episode)

Laura Silverman

as Kristin (1 episode)

From Wikipedia, the free encyclopedia. Laura Jane Silverman (born June 10, 1966, in Bedford, New Hampshire) is an Am...

Christine Parks

as Humanities Department Chair (1 episode)

Jake Robards

as Landlubbers (voice) (1 episode)

Michael Genet

as Thomas' Surgeon (1 episode)

A.C. Peterson

as Gene Diogenes (1 episode)

A.C. Peterson is known for Narc (2002), Shanghai Noon (2000) and Shooter (2007).

Christopher J. Hanke

as Thad (1 episode)

James Quattrochi

as Bus Driver (1 episode)

Brandon J. Dirden

as Kyle's Dad (1 episode)

Katt Masterson

as Doreen (1 episode)

Jason Furlani

as Larry Penn (1 episode)

Kate Grimes

as English Professor (1 episode)

Joseph Ragno

as Henrey Hood (1 episode) , Henrey Rood (1 episode)

Joseph Ragno was born on March 11, 1936 and is currently 88 years old.

Jaiden Klein

as Marie Sexton (2 episodes)

Chelsea Sheets

as Brunette (1 episode)

Matt Helm

as Young Leo (2 episodes)

Felix Solis

as Nurse (1 episode)

Felix Solis was born on September 17, 1971 and is currently 53 years old.

Joe Grifasi

as Steve Falice (1 episode)

Derek Goh

as 17-19 Year Old Dominick & Thomas Acting Double (2 episodes)

Raymond Neil Hernandez

as Omar (1 episode)

Simone Coppo

as Vincenzo Tempesta (1 episode)

Sean Cullen

as Dr. Yates (1 episode)

Sean J. Cullen is an American actor.

Federico Dordei

as Nunzio Tucci (1 episode)

Federico Dordei is an actor based in Los Angeles. He was born in Amman, Jordan. At the age of five, his family moved to Rome.

Agatha Nowicki

as Angie Constantine (2 episodes)

Shannon Plumb

as Charlotte (1 episode)

Tatanka Means

as Nabby Drinkwater (2 episodes)

Wayne J. Miller

as Mourner Wayne (1 episode)

Thomas Gionet-Lavigne

as Ray's Orderly (1 episode)

Philip Ettinger

as Early Adulthood Dominick Birdsey / Thomas Birdsey (2 episodes)

Aisling Franciosi

as Young Dessa Constantine (2 episodes)

Destry Allyn Spielberg

as Dr. Hume's Daughter (1 episode)

Roberta Riganò

as Ignazia Tempesta (1 episode)

Michael Simon Hall

as Stuart Feinstein (1 episode)

Al Linea

as Abruzzi (1 episode)

Richard Fitch

as Mill Foreman (1 episode)

Tim Ruddy

as Robocop (1 episode)

Morgan Sullivan

as Office Buddy (1 episode)

María Gonzalez

as Ma's Oncology Nurse (1 episode)

Rachel B. Joyce

as Jeanette (1 episode)

Paul Coleman

as Support Group Counselor (1 episode)

Annie Fitzgerald

as Miss Hanker (2 episodes)

Acahkos Johnson

as Penny Ann Drinkwater (2 episodes)

Charles Reina

as Channy (2 episodes)

Violet Adams

as Bunny Borsa (2 episodes)

Oliver Patnode

as Otero (2 episodes)

Irene Muscara

as Prosperina Tucci (2 episodes)

Adrienne R. Williams

as Mrs. Birdsall (2 episodes)

Zaria Degenhardt

as 11 Year Old Concettina (1 episode)

Mark A. Gamma

as Mourner Mark (1 episode)

Alexander Hacker

as Templeton (1 episode)

Robert Mladinich

as Paddy Wagon Officer (1 episode)

Crew of I Know This Much Is True

Discover the backstage crew of I Know This Much Is True →

I Know This Much Is True